منابع مشابه
Zoonotic Potential of Simian Arteriviruses.
Wild nonhuman primates are immediate sources and long-term reservoirs of human pathogens. However, ethical and technical challenges have hampered the identification of novel blood-borne pathogens in these animals. We recently examined RNA viruses in plasma from wild African monkeys and discovered several novel, highly divergent viruses belonging to the family Arteriviridae. Close relatives of t...
متن کاملDivergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques
UNLABELLED Simian hemorrhagic fever (SHF) is a highly lethal disease in captive macaques. Three distinct arteriviruses are known etiological agents of past SHF epizootics, but only one, simian hemorrhagic fever virus (SHFV), has been isolated in cell culture. The natural reservoir(s) of the three viruses have yet to be identified, but African nonhuman primates are suspected. Eleven additional d...
متن کاملPathogenesis and immune response of nonporcine arteriviruses versus porcine arteriviruses
The pathogenesis and immune response of pigs infected with porcine reproductive and respiratory syndrome virus (PRRSV) are not completely understood. PRRSV, along with equine viral arteritis (EAV), lactate dehydrogenase elevating virus of mice (LDV), and simian hemorrhagic fever virus (SHFV), are members of the genus Arteriviridae. This review summarizes the similarities and the differences fou...
متن کاملSpecific Detection of Two Divergent Simian Arteriviruses Using RNAscope In Situ Hybridization
Simian hemorrhagic fever (SHF) is an often lethal disease of Asian macaques. Simian hemorrhagic fever virus (SHFV) is one of at least three distinct simian arteriviruses that can cause SHF, but pathogenesis studies using modern methods have been scarce. Even seemingly straightforward studies, such as examining viral tissue and cell tropism in vivo, have been difficult to conduct due to the abse...
متن کاملHistorical Outbreaks of Simian Hemorrhagic Fever in Captive Macaques Were Caused by Distinct Arteriviruses.
Simian hemorrhagic fever (SHF) is lethal for macaques. Based on clinical presentation and serological diagnosis, all reported SHF outbreaks were thought to be caused by different strains of the same virus, simian hemorrhagic fever virus (SHFV; Arteriviridae). Here we show that the SHF outbreaks in Sukhumi in 1964 and in Alamogordo in 1989 were caused not by SHFV but by two novel divergent arter...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2016
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.01433-15